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Apoptosis, or programmed cell death, is an essential process that ensures an organism’s health by eliminating damaged or aberrant cells.
Caspase Assays for Flow Cytometry
A distinctive feature of the early stages of apoptosis is the activation of caspase enzymes, which participate in the cleavage of protein substrates and in the subsequent disassembly of the cell. We provide a series of caspase assays that allow the simple detection of active caspases in living cells by flow cytometry.
Apoptosis Assays for Flow Cytometry
Apoptosis, a form of programed cell death, is directed by activated caspases. Caspases are cysteine proteases that can cleave other proteins, and upon activation, create a positive-feedback cascade, which ensures the cell will undergo apoptosis.
Apoptosis, or programmed cell death, is an essential process by which multi-cellular organisms ensure that critically damaged or mutated cells are removed. The process is regulated by a complex interplay of proteins and, until reaching “the point of no return”, can be halted or reversed at any point.
Apoptosis, a programmed cell death mechanism, is an essential process in embryogenesis and development. The process is also critical for ensuring an organism’s health by removing aberrant or damaged cells.
Apoptosis is a highly regulated process of programmed cell death which, unlike necrosis, does not promote inflammatory responses and is beneficial to an organism.
Apoptosis and cell viability
Detection of apoptosis and cell viability by flow cytometry