The tumor microenvironment explained plus research resources
Immuno-oncology is the interaction between the immune system and cancerous cells (tumors). Immuno-oncology research is not only investigating how the immune system reacts to cancerous cells and how the cancerous cells respond, but also how the immune system can be manipulated to effectively target tumors and eradicate them
For detailed information on immuno-oncology read our mini-review entitled “Understanding immuno-oncology – the interplay between the immune system and cancer”.
It is not fully understood exactly how the immune system and the cancerous cells interact with each other within the tumor microenvironment. To aid understanding of this complex process, Dunn et al. (2002) proposed that there are three distinct phases to eventual tumor survival called the three “E” of immunoediting.