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BioLegend Human Th17 Flow™ Kit

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Th17 cells are a subset of CD4+ T cells defined by their ability to produce the cytokines IL-17, IL-17F and IL-22. Th17 cells participate in normal epithelial immunity, their dysregulation is implicated in psoriasis, multiple sclerosis, systemic lupus erythmatosis, rheumatoid arthritis, and inflammatory bowel disease.

BioLegend’s human Th17 flow kit is designed and formulated specifically for one-step intracellular immunofluorescence staining and flow cytometric analysis of Th17 cells in a mixed cell population. This kit is composed of fluorochrome conjugated anti-human CD3, CD4 and IL-17 antibodies, isotype control and the critical buffers. It is easy to use for identification of Th17 cells.

Clone: UCHT1/RPA-T4/BL168

Isotype: Mouse IgG1,κ / IgG1,κ / IgG1,κ

Reactivity: Human


CD3 FITC

PMA/ionomycin-stimulated (6hr) human peripheral blood lymphocytes stained with Human Th17 flow(TM) kit. Dot plot analysis is derived from gated in CD3+ cell population.

References:

1. King C, et al. 2004 Cell 117:265.
2. Betelli E, et al. 2006 Nature 441:235.
3. Betelli E, et al. 2007 Nat. Imm. 8:345.
4. Wilson NJ, et al. 2007 Nat. Imm. 8:950.